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Table 2 Adjusted β estimates from linear regression analyzing the association between Hp genotype and square root transformed CAC volume, stratified by the presence of CAC at baseline

From: Haptoglobin genotype predicts development of coronary artery calcification in a prospective cohort of patients with type 1 diabetes

   Adjusting for age and sex only Including covariates from backwards selection model*
Characteristic   β estimate p -value β estimate p -value
Hp genotype * diabetes interaction*presence of CAC at baseline interaction   N/A 0.001 N/A 0.001
   CAC not present at the baseline visit Hp 2-2 vs. 2-1/1-1 in patients with diabetes 0.82 0.03 0.74 0.05
  Hp 2-2 vs. 2-1/1-1 in controls without diabetes 0.67 0.2 0.83 0.11
   CAC present at the baseline visit Hp 2-2 vs. 2-1/1-1 in patients with diabetes -0.34 0.3 -0.31 0.33
  Hp 2-2 vs. 2-1/1-1 in controls without diabetes -2.02 0.52 0.24 0.7
Age   0.11 < 0.0001 0.1 < 0.0001
Female vs. male   -1.17 < 0.0001 0.22 0.001
Systolic blood pressure   N/A 0.01 < 0.0001
HDL cholesterol   N/A 0.01 0.003
  1. * Adjusting for age, sex, systolic blood pressure and HDL-cholesterol
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Cardiovascular Diabetology

ISSN: 1475-2840