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Table 1 Baseline characteristics in study subjects with 6 year progression data and Hp genotype data by diabetes status

From: Haptoglobin genotype predicts development of coronary artery calcification in a prospective cohort of patients with type 1 diabetes

Characteristic Study subjects with type 1 diabetes   Control subjects without type 1 diabetes  
  6 Year CAC Progression ≥ 2.5 6 Year CAC Progression < 2.5   6 Year CAC Progression ≥ 2.5 6 Year CAC Progression < 2.5  
  n = 178 n = 258   n = 150 n = 376  
CAC present at baseline visit 113(63) 37(14) * 86(57) 51(14) *
Haptoglobin genotype 2-2 76(43) 89(35)   46(31) 139(37)  
Mean 6 year change in CAC volume 7.4 ± 4.4 0.4 ± 0.8 * 5.8 ± 3.1 0.3 ± 0.7 *
Female 78(44) 160(62) * 41(27) 223(59) *
Mean age (years) 40.1 ± (8.1) 34.0 ± 8.2) * 45.2 ± 7.3) 39.0 ± 8.5 *
Mean diastolic blood pressure (mmHg) 78.0 ± 9.0 76.3 ± 8.4 * 83.2 ± 8.9 77.2 ± 7.6 *
Mean systolic blood pressure (mmHg) 120.2 ± 13.6 113.9 ± 12.1 * 120.4 ± 12.7 111.6 ± 11.1 *
Mean body mass index (kg/m2) 26.7 ± 4.3 25.6 ± 4.0 * 28.2 ± 4.8 25.3 ± 4.4 *
Mean LDL cholesterol (mmol/l) 2.7 ± 0.73 2.5 ± 0.7 * 3.1 ± 0.8 3.0 ± 0.8 *
Mean HDL cholesterol (mmol/l) 1.4 ± 0.4 1.5 ± 0.4 * 1.2 ± 0.3 1.4 ± 0.4 *
Mean triglycerides (mmol/l) 1.1 ± 0.01 1.0 ± 0.5 * 1.8 ± 1.2 1.3 ± 0.7 *
Mean HbA1c (%) 8.0 ± 1.2 7.8 ± 1.2   5.6 ± 0.4 5.4 ± 0.4 *
Ever smoker 48(27) 39(15) * 27(18) 86(23)  
  1. * p-value less than 0.05 comparing CAC progression in individuals with type 1 diabetes and control subjects separately
  2. Data are presented as mean ± sd or as n (%)