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Table 1 Hemodynamic parameters from control, diabetic rats and diabetic rats treated with AZL (5 mg kg-1 day-1)

From: Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis

Parameters

Control

(n = 10)

STZ*

(n = 10)

AZL** (5 mg/kg/day) (n = 12)

Systolic Pressure (mm Hg)

138.1 ± 4.7

93.8 ± 4.1

124.6 ± 8.9

Diastolic Pressure (mm Hg)

85.8 ± 6.2

64.0 ± 3.5

82.5 ± 7.1

Systolic duration (s)

0.085 ± 0.01

0.140 ± 0.01

0.084 ± 0.01

Diastolic duration (s)

0.117 ± 0.02

0.297 ± 0.02

0.127 ± 0.01

Heart rate (BPM)

323.3 ± 20.9

244.9 ± 10.8

312.2 ± 14.1

LV+dp/dt (mm Hg/s)

5861.4 ± 729.5

3219.3 ± 297.8

6098.6 ± 395.4

LV-dp/dt (mm Hg/s)

-6846.8 ± 752.1

-3553.0 ± 437.3

-7015.9 ± 391.5