Table 3 Parameter estimates for additive genetics (A), common environmental (C) and unique environmental (E) influences on cardiometabolic risk factors (A-C-E univariate model analysis)
From: Effect of genetic and environmental influences on cardiometabolic risk factors: a twin study
Parameter estimates | ||||
|---|---|---|---|---|
„A" Additive genetics (95% CI) | „C" Common environmental (95% CI) | „E" Unique environmental (95% CI) | ||
Weight | Model-1 | 88.1% (66.0 - 94.0) | 0.0% (0.0 - 56.8) | 11.9% (6.9 - 20.1) |
Waist circumference | Model-1 | 71.0% (17.7 - 91.8) | 15.5% (0.0 - 68.0) | 13.5% (6.5 - 23.9) |
Systolic blood pressure | Model-l | 59.0% (35.6 - 74.1) | 0.0% (0.0 - 0.0) | 41.0% (26.5 - 58.2) |
Model-2 | 57.1% (27.4 - 73.5) | 0.0% (0.0 - 65.9) | 42.9% (28.9 - 61.1) | |
Diastolic blood pressure | Model-1 | 60.4% (25.0 - 75.0) | 0.0% (0.0 - 36.2) | 39.6% (26.5 - 55.8) |
Model-2 | 57.7% (23.7 - 74.4) | 0.0% (0.0 - 65.6) | 42.3% (27.8 - 60.2) | |
Serum total cholesterol | Model-1 | 0.0% (0.0 - 65.5) | 50.1% (35.6 - 65.5) | 49.9% (33.7 - 64.8) |
Model-2 | 0.0% (0.0 - 70.2) | 46.8% (30.4 - 64.2) | 53.2% (35.8 - 69.3) | |
Serum HDL-cholesterol | Model-1 | 36.4% (3.9 - 69.5) | 47.6% (14.9 - 71.9) | 16.0% (9.4 - 23.1) |
Model-2 | 27.1% (0.0 - 62.1) | 58.1% (25.1 - 81.8) | 14.9% (8.3 - 23.0) | |
Serum triglycerides | Model-1 | 35.6% (0.0 - 68.6) | 17.1% (0.0 - 56.7) | 47.3% (28.9 - 66.9) |
Model-2 | 44.1% (22.2 - 65.1) | 0.0% (0.0 - 0.0) | 55.9% (34.8 - 77.6) | |
Fasting blood glucose | Model-1 | 0.0% (0.0 - 57.8) | 53.1% (34.8 - 69.3) | 46.9% (33.6 - 61.2) |
Model-2 | 0.0% (0.0 - 34.4) | 57.1% (36.4 - 74.8) | 42.9% (28.4 - 59.8) | |
Fasting insulin | Model-1 | 4.2% (0.0 - 60.4) | 47.1% (18.1 - 69.0) | 48.7% (30.1 - 67.8) |
Model-2 | 0.1% (0.0 - 62.8) | 45.4% (13.6 - 68.1) | 54.5% (34.2 - 77.6) | |
Serum creatinine | Model-1 | 62.3% (44.9 - 78.4) | 0.0% (0.0 - 0.0) | 37.7% (21.6 - 53.9) |
Model-2 | 64.1% (34.6 - 78.5) | 0.0% (0.0 - 56.2) | 35.9% (22.2 - 51.8) | |
Serum uric acid | Model-1 | 12.4% (0.0 - 48.1) | 56.7% (25.7 - 74.2) | 30.9% (20.5 - 45.8) |
Model-2 | 22.7% (0.0 - 74.5) | 46.0% (0.0 - 71.8) | 31.3% (18.6 - 46.1) | |
Fibrinogen | Model-1 | 66.2% (41.1 - 83.5) | 0.0% (0.0 - 25.1) | 33.8% (20.8 - 50.3) |
Model-2 | 59.9% (20.5 - 78.5) | 3.4% (0.0 - 57.7) | 36.7% (23.0 - 57.3) | |
Serum homocysteine | Model-1 | 0.0% (0.0 - 69.9) | 72.4% (53.7 - 80.6) | 27.6% (19.4 - 45.1) |
Model-2 | 0.0% (0.0 - 46.9) | 71.8% (50.5 - 79.7) | 28.2% (20.3 - 47.9) | |
Serum C-reactive protein | Model-1 | 66.0% (26.0 - 87.0) | 0.0% (0.0 - 43.4) | 34.0% (15.0 - 59.1) |
Model-2 | 51.9% (0.0 - 79.4) | 0.0% (0.0 - 52.4) | 48.1% (20.7 - 81.6) | |