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Table 3 Parameter estimates for additive genetics (A), common environmental (C) and unique environmental (E) influences on cardiometabolic risk factors (A-C-E univariate model analysis)

From: Effect of genetic and environmental influences on cardiometabolic risk factors: a twin study

   Parameter estimates
   „A" Additive genetics
(95% CI)
„C" Common environmental
(95% CI)
„E" Unique environmental
(95% CI)
Weight Model-1 88.1% (66.0 - 94.0) 0.0% (0.0 - 56.8) 11.9% (6.9 - 20.1)
Waist circumference Model-1 71.0% (17.7 - 91.8) 15.5% (0.0 - 68.0) 13.5% (6.5 - 23.9)
Systolic blood pressure Model-l 59.0% (35.6 - 74.1) 0.0% (0.0 - 0.0) 41.0% (26.5 - 58.2)
  Model-2 57.1% (27.4 - 73.5) 0.0% (0.0 - 65.9) 42.9% (28.9 - 61.1)
Diastolic blood pressure Model-1 60.4% (25.0 - 75.0) 0.0% (0.0 - 36.2) 39.6% (26.5 - 55.8)
  Model-2 57.7% (23.7 - 74.4) 0.0% (0.0 - 65.6) 42.3% (27.8 - 60.2)
Serum total cholesterol Model-1 0.0% (0.0 - 65.5) 50.1% (35.6 - 65.5) 49.9% (33.7 - 64.8)
  Model-2 0.0% (0.0 - 70.2) 46.8% (30.4 - 64.2) 53.2% (35.8 - 69.3)
Serum HDL-cholesterol Model-1 36.4% (3.9 - 69.5) 47.6% (14.9 - 71.9) 16.0% (9.4 - 23.1)
  Model-2 27.1% (0.0 - 62.1) 58.1% (25.1 - 81.8) 14.9% (8.3 - 23.0)
Serum triglycerides Model-1 35.6% (0.0 - 68.6) 17.1% (0.0 - 56.7) 47.3% (28.9 - 66.9)
  Model-2 44.1% (22.2 - 65.1) 0.0% (0.0 - 0.0) 55.9% (34.8 - 77.6)
Fasting blood glucose Model-1 0.0% (0.0 - 57.8) 53.1% (34.8 - 69.3) 46.9% (33.6 - 61.2)
  Model-2 0.0% (0.0 - 34.4) 57.1% (36.4 - 74.8) 42.9% (28.4 - 59.8)
Fasting insulin Model-1 4.2% (0.0 - 60.4) 47.1% (18.1 - 69.0) 48.7% (30.1 - 67.8)
  Model-2 0.1% (0.0 - 62.8) 45.4% (13.6 - 68.1) 54.5% (34.2 - 77.6)
Serum creatinine Model-1 62.3% (44.9 - 78.4) 0.0% (0.0 - 0.0) 37.7% (21.6 - 53.9)
  Model-2 64.1% (34.6 - 78.5) 0.0% (0.0 - 56.2) 35.9% (22.2 - 51.8)
Serum uric acid Model-1 12.4% (0.0 - 48.1) 56.7% (25.7 - 74.2) 30.9% (20.5 - 45.8)
  Model-2 22.7% (0.0 - 74.5) 46.0% (0.0 - 71.8) 31.3% (18.6 - 46.1)
Fibrinogen Model-1 66.2% (41.1 - 83.5) 0.0% (0.0 - 25.1) 33.8% (20.8 - 50.3)
  Model-2 59.9% (20.5 - 78.5) 3.4% (0.0 - 57.7) 36.7% (23.0 - 57.3)
Serum homocysteine Model-1 0.0% (0.0 - 69.9) 72.4% (53.7 - 80.6) 27.6% (19.4 - 45.1)
  Model-2 0.0% (0.0 - 46.9) 71.8% (50.5 - 79.7) 28.2% (20.3 - 47.9)
Serum C-reactive protein Model-1 66.0% (26.0 - 87.0) 0.0% (0.0 - 43.4) 34.0% (15.0 - 59.1)
  Model-2 51.9% (0.0 - 79.4) 0.0% (0.0 - 52.4) 48.1% (20.7 - 81.6)
  1. Model-1: values corrected for age and gender
  2. Model-2: values corrected for age, gender, waist circumference and body mass index