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Figure 5 | Cardiovascular Diabetology

Figure 5

From: Effects of granulocyte-colony stimulating factor (G-CSF) on diabetic cardiomyopathy in Otsuka Long-Evans Tokushima Fatty rats

Figure 5

The ultrastructure of saline-treated sucrose contained water fed OLETF rat (OLETF (+/-)) myocardium displays deposition of collagen fibers in pericapillary region and swelling of mitochondria in cardiac cells, whereas G-CSF treat rats (OLETF (+/+)) reveals absence of collagen deposition and relatively decreased number of abnormal mitochondria. Note the disruption or distortion of cristae network of the enlarged mitochondria in non-treated sucrose fed group (inset). N: nucleus, R: red blood cell, M: mitochondria, arrow: collagen fiber. A. OLETF (+/-); OLETF rat fed on sucrose water and treated with saline, B. OLETF (+/+); OLETF rat fed on sucrose water and treated with G-CSF.

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Cardiovascular Diabetology

ISSN: 1475-2840