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Table 2 Baseline characteristics of CAD and NCAD groups before surgery

From: Association of chemerin mRNA expression in human epicardial adipose tissue with coronary atherosclerosis

 

CAD (n = 37)

NCAD (n = 16)

P

Age (years)

59.1 ± 8.0

54.3 ± 9.4

NS

Male (%)

30 (81.1)

12 (75.0)

NS

Hypertension (%)

27 (73.0)

3 (18.8)

< 0.001

T2 DM (%)

11 (29.7)

1 (6.2)

NS

BMI (kg/m2)

27.1 ± 3.4

24.3 ± 2.6

0.004

Waist circumference (cm)

94.7 ± 9.2

85.5 ± 9.8

0.002

LVEF (%)

56.2 ± 10.1

60.1 ± 8.1

NS

Systolic blood pressure (mmHg)

129.3 ± 20.7

127.1 ± 19.5

NS

Diastolic blood pressure (mmHg)

78.1 ± 12.4

79 ± 14.0

NS

Aspirin (%)

16 (43.2)

0 (0)

0.005

Nitrates (%)

37 (100)

0 (0)

< 0.001

ACEIs/ARBs (%)

22 (59.5)

9 (56.2)

NS

Statins (%)

25 (67.6)

0 (0)

< 0.001

β-blockers (%)

35 (94.6)

3 (18.8)

< 0.001

Calcium channel blockers (%)

13 (35.1)

0 (0)

0.017

Insulin (%)

5 (13.5)

1 (6.2)

NS

Oral hypoglyceimic agents (%)

9 (24.3)

1 (6.2)

NS

Diuretics (%)

2 (5.4)

16 (100)

< 0.001

Antibiotics (%)

6 (16.2)

4 (25.0)

NS

Fasting glucose (mmol/L)

6.08 (5.25, 7.45)

5.19 (4.86, 5.51)

0.002

HbA1C (%)

6.3 ± 0.8

6.0 ± 0.6

NS

Fasting insulin (μU/mL)

4.67 (2.43, 45.75)

2.27 (1.77, 3.06)

0.031

HOMA-IR

1.43 (0.69, 1.32)

0.53 (0.44, 0.68)

0.013

Total cholesterol (mmol/L)

4.44 ± 1.00

4.83 ± 0.73

NS

HDL-C (mmol/L)

1.07 ± 0.24

1.25 ± 0.22

0.014

LDL-C (mmol/L)

2.68 ± 0.81

2.89 ± 0.53

NS

Triglycerides (mmol/L)

1.88 ± 1.09

1.77 ± 1.49

NS

Urea nitrogen (mmol/L)

6.82 ± 2.58

7.67 ± 2.46

NS

Serum creatinine (μmol/L)

89.9 ± 21.3

83.5 ± 20.1

NS

Uric acid (μmol/L)

380.2 ± 111.1

393.3 ± 96.8

NS

hsCRP (mg/L)

1.95 (0.98, 6.75)

1.07 (0.51, 1.66)

0.003

  1. Data are presented as mean ± SD, median (lower quartile, upper quartile), or number (%), P value represents CAD group vs. NCAD group. Abbreviations: CAD, coronary artery disease; T2DM, type 2 diabetes; BMI: body mass index; LVEF, left ventricular ejection fraction; ACEIs: angiotensin converting enzyme inhibitors; ARBs: angiotensin II type 1 receptor blockers; HbA1C, hemoglobin A1C; HOMA-IR: homeostasis model assessment of insulin resistance; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; hsCRP, high sensitivity C-reactive protein; NS, non-significance.