Skip to main content

Table 1 Characteristics of the experimental groups at sacrifice (12 weeks).

From: Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure

  

Sham

N = 8

MI

N = 10

MI-VI

N = 9

MI-VL

N = 9

A

BW (g)

(baseline)

321 ± 9

313 ± 5

321 ± 2

306 ± 4

 

BW (g)

(12 week)

446 ± 15

449 ± 11

436 ± 5

450 ± 7

 

LVW (g)

(12 week)

0.93 ± 0.03

1.05 ± 0.03*

0.97 ± 0.02

1.08 ± 0.03*

 

LVW/BW

2.00 ± 0.05

2.34 ± 0.09**

2.22 ± 0.05

2.39 ± 0.05**

B

Glucose (mmol/L)

(3 week)

9.0 ± 0.6

8.0 ± 0.5

7.8 ± 0.3

9.5 ± 0.4

 

Glucose (mmol/L)

(6 week)

7.2 ± 0.2

7.3 ± 0.3

7.1 ± 0.1

7.7 ± 0.2

 

Glucose (mmol/L)

(12 week)

8.0 ± 0.3

7.3 ± 0.2

8.0 ± 0.3

7.6 ± 0.2

 

Cholesterol (mmol/L)

1.49 ± 0.09

1.48 ± 0.04

1.45 ± 0.08

1.39 ± 0.07

 

Triglycerides (mmol/L)

0.95 ± 0.19

1.12 ± 0.13

0.84 ± 0.11

0.86 ± 0.12

  1. Data are presented as means ± SEM; N indicates number of animals; BW, body weight; LVW, left ventricle weight; LVW/BW, left ventricle weight/body weight ratio.**P < 0.01 vs. Sham.*P < 0.05 vs. Sham.