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Table 1 Anthropometric data and comorbidities in 137 extremely obese subjects according to presence or absence of obstructive sleep apnea

From: Type 2 diabetes and pre-diabetes are associated with obstructive sleep apnea in extremely obese subjects: A cross-sectional study

Variables All participants OSA no OSA yes p-value
N 137 53 (39%) 84 (61%)  
Gender (male/female) 36/101 (26/74%) 7/46 (19/45%) 29/55 (81/55%) 0.006
Age (years) 43 (11) 36 (8.8) 48 (9.8) <0.001
Smokers 36 (26%) 15 (28%) 21 (25%) 0.830
Alcohol consumption (units/week) 1.1 (1.8) 0.9 (1.5) 1.2 (2.1) 0.350
Anthropometric measures     
BMI (kg/m²) 46.9 (5.7) 46.3 (5.2) 47.2 (6.1) 0.377
Weight (kg) 136 (22.2) 134 (22.3) 137 (22.1) 0.324
Neck (cm) 42 (4.2) 40.5 (3.8) 43.1 (4.1) <0.001
Waist (cm) 135 (14) 132 (13.6) 136 (13.5) 0.097
Hip (cm) 139 (12) 140 (10.0) 138 (13.2) 0.389
Waist-to-hip ratio 0.98 (0.09) 0.9 (0.1) 1.0 (0.1) 0.005
Blood pressure (mean value, 24-hour ambulatory pressure)    
Systolic (mmHg) 135 (17) 128 (14) 139 (18) <0.001
Diastolic(mmHg) 84 (10) 81 (10) 86 (10) 0.016
Comorbidities     
Coronary heart disease 5 (4%) 0 (0%) 5 (6%) 0.156
Hypertension 48 (35%) 10 (19%) 38 (45%) 0.002
Albuminuria     
Microalbuminuria 19 (14%) 4 (8%) 15 (19%) 0.126
Macroalbuminuria 4 (3%) 0 (0%) 4 (5%) 0.153
Hypothyreosis 18 (13%) 6 (11%) 12 (14%) 0.796
Anxiety and/or depression 56 (41%) 28 (53%) 28 (33%) 0.032
Asthma 35 (26%) 16 (30%) 19 (23%) 0.421
Chronic obstructive pulmonary disease 5 (4%) 2 (4%) 3 (4%) 1.000
Inflammation     
Leptin (microg/l) 60.9 (19.3) 66.6 (16.4) 57.4 (20.3) 0.001
Visfatin (ng/ml) 26.0 (63.2) 33.2 (97.6) 21.5 (23) 0.692
High sensitive CRP (mg/l) 3.0 (2.6) 3.5 (3.2) 2.6 (2.1) 0.231
Osteoprotegerin (microg/ml)( 2644 (1640) 2381 (1413) 2809 (1757) 0.099
Adiponectin (pg/ml) 5510 (3368) 5278 (2633) 5656 (3767) 0.954
IL1Ra (pg/ml) 964 (1964) 877 (1913) 1020 (2004) 0.396
Leptin:adiponectin ratio (ng/ml:pg/ml) 0.016 (0.012) 0.017 (0.012) 0.015 (0.012) 0.096
  1. Variables are given as either mean (SD) or proportions (%). Statistical analysis: Fisher's exact test (categorical data), independent samples t-test (continuous data) and Mann-Whitney U test (non-parametric, continuous data).