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Table 5 Hazard ratios for the significant association between ADIPOR2 SNPs and the development of T2DM during follow-up of median 7 years

From: Association of ADIPOR2 gene variants with cardiovascular disease and type 2 diabetes risk in individuals with impaired glucose tolerance: the Finnish Diabetes Prevention Study

  

HR (95% CI), p/qa

HR (95% CI), p/qb

rs11061946

CC (428)

1

1

 

CT (49)

0.706 (0.412- 1.211), 0.206/0.517

0.872 (0.536- 1.417), 0.579/0.596

 

TT (5)

5.538 (2.014- 15.226), 0.001/0.369

 

rs11061973

GG (401)

1

1

 

GA (76)

0.951 (0.636- 1.423), 0.808/0.657

1.061 (0.724- 1.557), 0.761/0.657

 

AA (5)

5.683 (2.066- 15.636), 0.001/0.369

 
  1. All analyses were adjusted for CVD at baseline, age, sex, baseline waist circumference, baseline total to HDL cholesterol ratio, smoking status, systolic blood pressure and study group; Correction for multiple hypothesis testing in single SNP analyses was performed by using FDR, denoted as q-value; aAdditive inheritance model for single SNP analyses; bDominant inheritance model for single SNP analyses.
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Cardiovascular Diabetology

ISSN: 1475-2840