Skip to main content

Table 4 Hazard ratios for the significant association between ADIPOR2 SNPs and the development of CVD during follow-up of median 10.2 years

From: Association of ADIPOR2 gene variants with cardiovascular disease and type 2 diabetes risk in individuals with impaired glucose tolerance: the Finnish Diabetes Prevention Study

   HR (95% CI), p/qa HR, 95% CI, p/qb
rs10848554 GG (358) 1 1
  GC (102) 1.510 (0.957-2.382), 0.076/0.110 1.565 (1.004-2.440), 0.048/0.095
  CC (7) 2.919 (0.697-12.23), 0.143/0.150  
rs11061937 TT (207) 1 1
  TC (206) 0.568 (0.364-0.885), 0.012/0.095 0.595 (0.395-0.896), 0.013/0.095
  CC (54) 0.701 (0.353-1.390), 0.309/0.238  
rs1058322 CC (218) 1 1
  CT (201) 1.601 (1.021-2.509), 0.040/0.095 1.711 (1.114-2.627), 0.014/0.095
  TT (48) 2.300 (1.194-4.433), 0.013/0.095  
rs16928751 GG (364) 1 1
  GA (99) 1.677 (1.051-2.674), 0.030/0.095 1.756 (1.114-2.766), 0.015/0.095
  AA (4) 4.425 (1.042-18.79), 0.044/0.095  
  1. All analyses were adjusted for age, sex, baseline waist circumference, baseline 2-h plasma glucose and study group; Correction for multiple hypothesis testing in single SNP analyses was performed by using FDR, denoted as q-value; aAdditive inheritance model for single SNP analyses; bDominant inheritance model for single SNP analyses.