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Table 2 Metabolic parameters for each subject group

From: Novel adiponectin-resistin (AR) and insulin resistance (IRAR) indexes are useful integrated diagnostic biomarkers for insulin resistance, type 2 diabetes and metabolic syndrome: a case control study

 

Subjects

 

Variables

Control

(n = 208)

group A

MS

without T2DM

(n = 174)

group B

T2DM

without MS

(n = 171)

group C

T2DM

with MS

(n = 256)

group D

F-test; P-value

(A vs. B vs. C vs. D)

Total cholesterol (mmol/L)

5.03 (4.91, 5.14)

5.16 (5.03, 5.29)

4.68 (4.52, 4.85)

4.64 (4.50, 4.78)

12.412; 6.10 × 10-8

 

C***, D***

C***, D***

A***, B***

A***, B***

 

HDL cholesterol (mmol/L)

1.28 (1.25, 1.31)

1.07 (1.03, 1.10)

1.26 (1.22, 1.29)

1.04 (1.01, 1.07)

62.822; 1.70 × 10-36

 

B***, D***

A***, C***

B***, D***

A***, C***

 

LDL cholesterol (mmol/L)

3.14 (3.03, 3.26)

3.09 (2.95, 3.25)

2.88 (2.73, 3.04)

2.69 (2.57, 2.81)

10.656; 7.11 × 10-7

 

C**, D***

C*, D***

A**, B*

A***, B***

 

Triglyceride (mmol/L)

1.31 (1.25, 1.37)

2.20 (2.07, 2.34)

1.20 (1.12, 1.27)

2.02 (1.89, 2.16)

68.292; 2.40 × 10-39

 

B***, C*, D***

A***, C***

A*, B***, D***

A***, C***

 

Glucose (mmol/L)

5.13 (5.05, 5.23)

5.51 (5.39, 5.63)

8.04 (7.60, 8.50)

8.26 (7.94, 8.60)

118.021; 2.46 × 10-63

 

B***, C***, D***

A***, C***, D***

A***, B***

A***, B***

 

HbA1C (%)

5.63 (5.57, 5.69)

5.82 (5.76, 5.89)

8.07 (7.78, 8.36)

8.09 (7.90, 8.28)

225.382; 4.32 × 10-106

 

B***, C***, D***

A***, C***, D***

A***, B***

A***, B***

 

Insulin (μU/mL)

10.99 (10.05, 11.97)

19.94 (16.95, 23.42)

14.86 (12.76, 17.04)

24.32 (20.85, 27.95)

15.096; 1.45 × 10-9

 

B***, C**, D***

A***, C*

A**, B*, D**

A***, C**

 
  1. Data are expressed as mean (95% confident interval). ANCOVA test was used, followed by pairwise comparison using 1,000 stratified bootstrap samples with bias corrected and accelerated (BCa) 95% CI for multiple testing bias corrections due to deviation of normality. The p-value was also adjusted for covariate ages with stratified ethnicity. The location of statistically significant differences are displayed as group's name (A, B, C, or D). Significant levels: P* < 0.05, P** < 0.01, P*** < 0.001. Note: T2DM = type 2 diabetes; MS = metabolic syndrome.