Comparative effect of olmesartan and candesartan on lipid metabolism and renal function in patients with hypertension: a retrospective observational study

Table 3 Changes in adjusted laboratory test values during exposure period from baseline

Laboratory tests	Olmesartan (n = 168)			Candesartan (n = 266)			p value
	Mean	95% CI		Mean	95% CI
		Lower	Upper		Lower	Upper
Lipid metabolism
Δ Triglyceride (mmol/L)	-0.080	-0.185	0.024	0.132	0.025	0.239	0.0087*
Δ LDL-cholesterol (mmol/L)	-0.085	-0.146	-0.023	-0.065	-0.112	-0.017	0.6094
Δ Total cholesterol (mmol/L)	-0.091	-0.168	-0.015	-0.039	-0.106	0.028	0.3248
Renal function
Δ Urea nitrogen (mmol/L)	0.381	0.181	0.582	0.242	0.072	0.412	0.3059
Δ Creatinine (μmol/L)	2.378	1.264	3.492	2.608	1.397	3.828	0.7989
Δ Potassium (mmol/L)	0.078	0.035	0.122	0.042	0.009	0.076	0.1933

Δ indicates the mean change in laboratory test value during the exposure period from baseline. CI denotes confidence interval. *: p < 0.05 (candesartan vs olmesartan)

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