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Table 3 The relations between plasma OPG and the prevalence of significant CAD as defined by abnormal MPI and/or stenosis on CAG.

From: Osteoprotegerin and coronary artery disease in type 2 diabetic patients with microalbuminuria

Parameter

OR

95% CI

p-value

Study population as a whole (n = 200)

'Significant CAD'

   Unadjusted OPG (2rd tertile vs. 1st)

2.74

1.23-6.10

0.013

   Unadjusted OPG (3rd tertile vs. 1st)

4.24

1.93-9.31

0.0001

   Adjusted OPG (2rd tertile vs. 1st)

3.51

1.39-8.86

0.008

   Adjusted OPG (3rd tertile vs. 1st)

3.54

1.36-9.21

0.010

  1. Odds ratios (ORs) were assessed by logistic regression in univariate and multivariable analyses.
  2. Covariate adjustments included variables associated with significant CAD in univariate analysis (p < 0.05), including P-total cholesterol, P-creatinine, peripheral systolic blood pressure, vibratory perception threshold and heart rate variability.
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Cardiovascular Diabetology

ISSN: 1475-2840