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Table 5 Relative changes in gene expression connected with oxidative stress and inhibition of angiogenesis for white (WAT) and brown (BAT) adipose tissues of eNOS -/- and DDAH animals vs. control mice.

From: Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance

   WAT BAT
   eNOS-/- DDAH eNOS-/- DDAH
Anti-Angiogenic genes
Adhesion      
thrombospondin 1 Thbs1    
thrombospondin 2 Thbs2   
Collagen   ↑7subunits ↑3subunits   
    1 subunit   
laminin B1 Lamb1-1    
Laminin alpha Lama    
Laminin beta Lamb    
integrin alpha Itga6    
  Itga7    
  Itga8   
  Itgam   
MMP's     
tissue inhibitor of metalloproteinase Timp3     
  Timp4  
Apoptosis     
nuclear factor of kappa B Nfkbia   
caspase Casp7    
  Casp8    
BCL2-associated X protein Bax    
conserved helix-loop-helix ubiquitous kinase Chuk    
transformation related protein 53 Trp53    
BCL2-related ovarian killer protein Bok    
X-linked inhibitor of apoptosis    
Oxidative stress
Repression of ROS production     
cytochrome b-245, alpha polypeptide Cyba   
nuclear factor I/X Nfix     
glutathione S-transferase, theta 2 Gstt2    
Gtpase activating protein Gyp1a1    
monoamine oxidase A Maoa    
Adaptation against existing ROS     
FBJ osteosarcoma oncogene Fos  
superoxide dismutase 2 Sod  
glutathione S-transferase theta Gstt    
glutathione peroxidase 3 Gpx    
catalase Cat    
thioredoxin 2 Txn2    
  1. ↑ - upregulated genes; ↓ -downregulated genes; # - genes which expression was confirmed by real time PCR