From: Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice
db/m + vehicle | db/db + vehicle | db/db + silibinin | |
---|---|---|---|
8-weeks weight
(g) | 22.5 ± 0.5 | 33.0 ± 2.2* | 32.5 ± 2.7* |
12-weeks weight
(g) | 25.6 ± 1.2 | 38.4 ± 1.8* | 36.8 ± 1.9* |
Blood glucose (mg/dL) | 68.2 ± 7.6 | 220.8 ± 40.2** | 112.7 ± 22.8† |
Serum insulin (mU/L) | 6.8 ± 1.2 | 10.3 ± 0.8** | 7.5 ± 1.1† |
HOMA-IR | 1.1 ± 0.2 | 5.6 ± 0.5** | 2.1 ± 0.3†† |