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Figure 2 | Cardiovascular Diabetology

Figure 2

From: Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice

Figure 2

Vasomotor responses in isolated aorta. (A) Vasoconstriction to phenilephrine (PE); (B) vasodilatation to acetylcholine (ACh); (C) vasodilatation to sodium nitroprusside (SNP); (D) vasoconstriction to asymmetric NG, NG-dimethyl-L-arginine (ADMA). Vasoconstriction is expressed in % of high K+-induced tone in the same preparation; vasodilatation is expressed as residual tone in % of PE-induced preconstriction. **P < 0.01 versus db/m + vehicle; ††P < 0.01 versus db/db + vehicle.

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