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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway

Figure 4

Effects of GLP-1 on action potentials in isolated canine left ventricular cardiomyocytes. A, Extracellular perfusion of 5 nM GLP-1 (GLP-1) prolonged the action potential duration and the effect was removable after washing out of GLP-1 (Washout). B, GLP-1 at 5 nM prolonged the action potential durations measured at 50% (APD50) and 90% (APD90) repolarization. ΔAPD, the differences between control and 5 nM GLP-1. *, p < 0.05; **, p < 0.01; versus control.

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Cardiovascular Diabetology

ISSN: 1475-2840