Table 2 Laboratory parameters of type 2 diabetic participants and their relationships with levels of Ang-2 and sTie-2 after controlling for age and BMI

* HbA_1c (%)

7.6 (6-12.9)

^‡(r = 0.526, p < 0.000)

Fasting blood Glucose (mg/dl)

152 ± 55

^‡(r = 0.353, p < 0.005)

C-Peptide (ng/ml)

2.5 ± 1.3

NS

* Insulin (μU/ml)

11 (1-99.7)

^†(r = 0.355, p < 0.004), ^‡(r = 0.289, p < 0.02)

* HOMA-IR

4 (0-57.7)

^†(r = 0.334, p < 0.007), ^‡ (r = 0.322, p < 0.01)

Total cholesterol (mg/dl)

187 ± 47

NS

LDL-cholesterol (mg/dl)

102 ± 40

NS

* HDL-cholesterol (mg/dl)

44 (26-117)

NS

Triglyceride (mg/dl)

198 ± 109

^‡(r = 0.305, p < 0.01)

Creatinine (mg/dl)

1.09 ± 0.27

^†(r = 0.345, p < 0.003)

GFR (ml/min/1.73 m²)

66 ± 15

^†(r = -0.374, p < 0.001)

* CRP (mg/dl)

0.27 (0.01-3.2)

NS

Bilirubin (mg/dl)

0.62 ± 0.22

NS

* AST (U/l)

24 (12-53)

^‡(r = 0.452, p < 0.000)

ALT(U/l)

27 ± 11

^‡(r = 0.369, p < 0.002)

* GGT(U/l)

32 (8-165)

^†(r = 0.454, p < 0.000), ^‡(r = 0.483, p < 0.000)

* SHBG (nmol/l)

33 (12.8-189)

NS