Table 1 Clinical and demographic characteristics of type 2 diabetic participants and their relationships with levels of Ang-2 and Tie-2 after controlling for age and BMI

Sex (%)

47.7 (female)

NS

Age (years)

65 ± 7

^‡(r = -0.349, p < 0.002)

BMI (kg/m²)

32 ± 6

^†(r = 0.277, p < 0.01)

Waist to height ratio

0.66 ± 0.12

NS

Duration of diabetes (years)

15 ± 9

NS

* Ang-2 (pg/ml)

2955 (1349-9000)

^‡(r = 0.355, p < 0.002)

sTie-2 (ng/ml)

28.34 ± 7.58

^†(r = 0.355, p < 0.002)

Active smokers (%)

23

NS

Therapy

^†(p < 0.04)

Insulin therapy (%)

48.7

Oral anti-diabetic therapy (%)

51.3

Systolic blood pressure (mmHg)

145 ± 21

NS

Diastolic blood pressure (mmHg)

82 ± 14

^†(r = -0.259, p < 0.02)

Diabetic retinopathy (%)

3.8

NS

Microalbuminuria (%)

3.8

NS

Polyneuropathy (%)

50

^†(p < 0.01)

^#Macro-vascular complications (%)

29.1

^†(p < 0.009)