Men, N = 822 | Normal fasting plasma glucose | IFG | Type-2 diabetes or >125 mg/dL | P-value* | ||
---|---|---|---|---|---|---|
Characteristics | FBS <90 N = 200 | 90-99 N = 286 | 100-109 N = 143 | 110-125 N = 63 | N = 130 | |
Age (years) | 57 ± 15 | 60 ± 14 | 63 ± 13 | 60 ± 12 | 66 ± 9 | <0.001 |
Body mass index (kg/m2) | 22.6 ± 2.9 | 23.6 ± 2.8 | 24.5 ± 3.1 | 24.7 ± 3.2 | 23.8 ± 2.7 | <0.001 |
Smoking status, % | 29.0/19.5/51.5 | 46.9/22.7/30.4 | 43.4/29.4/27.3 | 44.4/28.6/27.0 | 46.2/30.8/23.1 | <0.001 |
Alcohol consumption, % | 15.0/33.0/52.0 | 12.9/31.8/55.2 | 17.5/20.3/62.2 | 3.2/22.2/74.6 | 20.0/26.2/53.8 | 0.005 |
History of CVD, % | 7.0 | 9.1 | 10.5 | 9.5 | 15.4 | 0.160 |
Systolic blood pressure (mmHg) | 130 ± 17 | 140 ± 20 | 147 ± 18 | 147 ± 19 | 147 ± 20 | <0.001 |
Diastolic blood pressure (mmHg) | 80 ± 10 | 84 ± 11 | 87 ± 11 | 90 ± 12 | 87 ± 10 | <0.001 |
Antihypertensive medication, % | 13.5 | 22.4 | 32.9 | 33.3 | 33.8 | <0.001 |
Triglycerides (mg/dL) | 91 (66-133) | 94 (73-126) | 104 (75-142) | 105 (77-165) | 96 (71-162) | 0.014 |
HDL cholesterol (mg/dL) | 59 ± 14 | 59 ± 14 | 60 ± 16 | 59 ± 16 | 58 ± 16 | 0.880 |
LDL cholesterol (mg/dL) | 105 ± 31 | 111 ± 29 | 118 ± 34 | 107 ± 33 | 111 ± 33 | 0.003 |
Antilipidemic medication, % | 2.5 | 3.5 | 4.9 | 1.6 | 6.9 | 0.229 |
Serum uric acid (mg/dL) | 5.9 ± 1.2 | 6.0 ± 1.4 | 6.1 ± 1.4 | 6.2 ± 1.4 | 5.5 ± 1.4 | <0.001 |
Fasting plasma glucose (mg/dL) | 86 (83-88) | 94 (92-96) | 103 (101-105) | 115 (112-118) | 122 (100--150) | <0.001 |
Immuno-reactive insulin (μ U/mL) | 3.65 (2.00-5.48) | 4.60 (3.20-6.90) | 6.20 (3.50-8.30) | 6.60 (4.70-8.70) | 4.80 (3.30-8.20) | <0.001 |
Hypoglycemic medication, % | 0 | 0 | 0 | 0 | 25.4 | <0.001 |
HMW adiponectin (μ g/mL) | 3.65 (2.37-6.09) | 3.41 (1.97-5.52) | 3.66 (1.91-5.10) | 2.67 (1.70-4.99) | 3.03 (1.86-4.88) | 0.030 |
hsCRP (mg/dL) | 0.046 (0.026-0.096) | 0.046 (0.025-0.104) | 0.057 (0.028-0.112) | 0.069 (0.042-0.150) | 0.060 (0.035-0.117) | 0.033 |