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Table 1 Systemic effects of drug treatment in DH rats

From: Protein Kinase C inhibition ameliorates functional endothelial insulin resistance and Vascular Smooth Muscle Cell hypersensitivity to insulin in diabetic hypertensive rats

 

SD rat

DH rat

 

Vehicle

Vehicle

Capto

RBX

Body Weight (grams)

539.2 ± 43.3

573.8 ± 49.1

566.4 ± 46.6

566.1 ± 45.6

Glucose (mg/dl)

129.4 ± 8.65

284.5 ± 38.5*

278.7 ± 28.7*

284.0 ± 22.7*

Trigl yceride (mg/dl)

122.5 ± 18.14

135.2 ± 48.5

130.8 ± 50.8

98.2 ± 42.2

Insulin (mg/dl)

1.42 ± 0.462

2.23 ± 1.97*

2.07 ± 1.46*

1.50 ± 0.787

FFA (mg/dl)

223.6 ± 84.2

660.7 ± 170.6*

483.5 ± 152.6*

462.7 ± 145.4*

  1. Notes: FFA: free fatty acid; Capto: captopril treatment; RBX: ruboxistaurin treatment; SD: Sprague Dawley rat; DH: diabetic hypertension. * indicates statistical difference in comparison with control (P < 0.05).
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Cardiovascular Diabetology

ISSN: 1475-2840