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Figure 6 | Cardiovascular Diabetology

Figure 6

From: Protein Kinase C inhibition ameliorates functional endothelial insulin resistance and Vascular Smooth Muscle Cell hypersensitivity to insulin in diabetic hypertensive rats

Figure 6

Vascular contractile tension during vasoconstriction in response to α-adrenergic receptor agonist (phenylephrine, PE) and insulin. A: PE-induced vascular contraction. SD+V: Vehicle treated Sprague-Dawley rats. H+V: Vehicle treated IUPD hypertensive rats. H+C: Captopril treated IUPD hypertensive rats. B: Insulin-induced vascular contraction while eNOS was blocked with L-NAME. n = 6; *: P < 0.05 vs. vehicle treated of SD rats at the doses. #: P < 0.05 vs. vehicle treated SD rats using ANOVA.

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