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Figure 2 | Cardiovascular Diabetology

Figure 2

From: Protein Kinase C inhibition ameliorates functional endothelial insulin resistance and Vascular Smooth Muscle Cell hypersensitivity to insulin in diabetic hypertensive rats

Figure 2

The typical tracing curves of pressure and diameter versus time during vasoreactivity which were measured by isovolumic myograph. A: The endothelium-dependent dose-response vasorelaxation. The vessels were contracted by phenylephrine (PE) to approximate pressures and relaxed by a series of doses of acetylcholine (ACh) (top panel) or a series of doses of ACh following by a series doses of insulin (bottom panel). B: The dose-response vasoconstriction in response to PE (top panel) and insulin with presentation of L-NAME (bottom panel).

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Cardiovascular Diabetology

ISSN: 1475-2840