Variable | Total cohort | Serum non-HDL-C concentration (mg/dL)a | Â | ||
---|---|---|---|---|---|
 |  | 35-129 | 130-189 | 190-403 | P-valueb |
Unweighted sample size | 1,122 | 200 | 563 | 359 | Â |
Weighted % | 100.0 ± 0.0c | 16.0 ± 2.1 | 49.2 ± 2.6 | 34.8 ± 2.7 |  |
Follow-up length (yr) | 12.4 ± 0.3 | 12.9 ± 1.2 | 12.5 ± 0.3 | 11.9 ± 0.8 |  |
Serum non-HDL-C concentration (mg/dL) | 174.2 ± 2.9 | 106.7 ± 3.5 | 160.2 ± 1.0 | 225.1 ± 2.6 | <0.001 |
Demographic characteristics | Â | Â | Â | Â | Â |
Age (yr) | 60.3 ± 0.7 | 58.4 ± 3.1 | 60.2 ± 1.0 | 61.2 ± 0.9 | 0.39 |
Male (%) | 46.9 ± 2.5 | 60.9 ± 7.1 | 49.8 ± 3.7 | 36.4 ± 3.7 | 0.006 |
Non-Hispanic white (%) | 74.9 ± 2.0 | 68.9 ± 5.5 | 74.4 ± 2.5 | 78.3 ± 2.9 | 0.09 |
Less than high school (%) | 42.6 ± 3.0 | 38.5 ± 6.6 | 39.8 ± 4.2 | 48.5 ± 4.0 | 0.21 |
Diabetes duration (yr) | 9.4 ± 0.4 | 10.5 ± 1.0 | 9.0 ± 0.5 | 9.3 ± 0.6 | 0.30 |
CVD risk factors | Â | Â | Â | Â | Â |
Current or former smokers (%) | 58.9 ± 2.4 | 58.1 ± 8.0 | 60.2 ± 3.2 | 57.5 ± 3.9 | 0.94 |
Alcohol consumption (times in previous month) | 4.5 ± 0.7 | 5.9 ± 1.9 | 4.7 ± 1.2 | 3.5 ± 1.0 | 0.26 |
Body mass index (kg/m2) | 30.1 ± 0.3 | 27.6 ± 0.6 | 30.3 ± 0.4 | 30.9 ± 0.5 | <0.001 |
Leisure-time physical activity (METS) | 80.6 ± 6.5 | 105.4 ± 19.5 | 81.0 ± 8.3 | 68.7 ± 8.8 | 0.10 |
Systolic blood pressure (mm Hg) | 134.0 ± 1.1 | 129.0 ± 2.4 | 132.6 ± 1.6 | 138.3 ± 2.0 | 0.007 |
Serum HDL-C (mg/dL) | 45.7 ± 0.8 | 53.1 ± 2.4 | 45.6 ± 1.0 | 42.4 ± 1.0 | <0.001 |
Glomerular filtration rate (mL/min per 1.73 m2) | 83.5 ± 1.2 | 85.9 ± 5.7 | 86.4 ± 1.3 | 78.3 ± 1.7 | 0.20 |
Serum glycated hemoglobin A1C (%) | 7.7 ± 0.1 | 7.4 ± 0.2 | 7.6 ± 0.1 | 7.9 ± 0.2 | 0.06 |
C-reactive protein ≥ 3.0 mg/L (%) | 50.4 ± 3.4 | 35.6 ± 6.5 | 50.0 ± 4.1 | 57.8 ± 4.4 | 0.003 |
Use of prescribed medicine to lower blood cholesterol (%) | 9.0 ± 1.3 | 4.2 ± 1.9 | 9.1 ± 2.3 | 11.1 ± 2.7 | 0.036 |