Table 1 Clinical characteristics

Age (years)

64 ± 10

68 ± 10

<0.001

Sex (men, %)

90 (52.9%)

130 (63.4%)

0.04

BMI (kg/m2)

25.7 ± 4.0

25.0 ± 3.2

0.037

Waist-to-hip ratio

0.93 ± 0.07

0.92 ± 0.08

NS

Systolic BP (mmHg)

137 ± 19

139 ± 23

NS

Diastolic BP (mmHg)

79 ± 11

78 ± 12

NS

Smoker (n, %)

44 (25.9%)

51 (24.9%)

NS

Hypertension (n, %)

113 (66.5%)

155 (75.6%)

0.051

Stroke (n, %)

17 (10.0%)

20 (9.8%)

NS

Duration of diabetes (years)

8 ± 7

8 ± 7

NS

Total Cholesterol (mmol/L)

4.55 ± 1.08

4.41 ± 1.16

NS

Triglyceride (mmol/L)

1.98 ± 1.70

1.98 ± 1.45

NS

HDL Cholesterol (mmol/L)

1.19 ± 0.32

1.14 ± 0.34

0.030

LDL Cholesterol (mmol/L)

2.73 ± 0.78

2.64 ± 0.91

NS

lipoprotein (a) (mg/L)

102 ± 158

238 ± 186

<0.001

BUN (mmol/L)

6.3 ± 2.6

7.2 ± 6.2

NS

Creatinine (umol/L)

74.5 ± 28.1

91.1 ± 39.6

<0.001

CrCl (ml/min)

44.2 ± 18.6

33.5 ± 14.6

<0.001

Uric acid (mg/L)

74.5 ± 28.1

91.1 ± 39.6

0.034

Fasting glucose (mmol/L)

7.7 ± 2.5

7.3 ± 2.7

NS

2 h Postprandial glucose (mmol/L)

13.1 ± 4.7

12.9 ± 4.2

NS

HbA1c (%)

8.1 ± 2.0

7.6 ± 1.4

0.012

Fasting insulin (mU/L)

10.1 ± 10.8

8.3 ± 7.8

NS

2 h Postprandial insulin (mU/L)

48.2 ± 48.7

39.4 ± 35.5

NS

hsCRP (mg/L)

6.7 ± 11.1

15.4 ± 15.9

<0.001

esRAGE (ng/ml)

0.31 ± 0.16

0.26 ± 0.18

<0.001

MRP8/14 (ug/ml)

8.2 ± 3.0

9.7 ± 3.6

<0.001