Phenotype | Prevalence | Families | Z Score | Lod | P | Empirical P |
|---|
Hypercholesterolemia
| 87.30% | 84 | 2.12 | 1.24 | 0.008 | 0.007 |
- Prevalence = phenotype prevalence among the family subjects studied; Families = families number analyzed; Z score = derived from the non-parametric linkage analysis by Merlin; Lod = Lod score derived from the non-parametric linkage analysis by Merlin; P = p-value; Empirical P = p-value derived from 1000 replicates by using the gene dropping method; Hypercholesterolemia defined by the presence of LDL ≥ 100 mg/dl in drug-naïve patients or by the presence of a diagnosis of hypercholesterolemia treated with a statin medication.
