Table 1 Characteristics of subjects according to serum amylase quartiles
From: Low serum amylase in association with metabolic syndrome and diabetes: A community-based study
| Â | Total | Q1 (Lowest) | Q2 | Q3 | Q4 (Highest) | P value |
|---|---|---|---|---|---|---|
n | 2,425 | 610 | 585 | 613 | 617 | Â |
Men, n (%) | 1,589 (65.5) | 428 (70.2) | 419 (71.6) | 376 (61.3) | 366 (59.3) | < 0.0001* |
Age, y | 53.8 ± 11.9 | 51.1 ± 11.0 | 51.9 ± 11.4 | 54.6 ± 12.1 | 57.4 ± 12.0 | < 0.0001 |
BMI, kg/m2 | 23.3 ± 3.2 | 24.3 ± 3.4 | 23.5 ± 3.1 | 23.1 ± 3.1 | 22.3 ± 2.9 | < 0.0001 |
Waist circumference, cm | 82.1 ± 8.8 | 84.6 ± 9.0 | 82.9 ± 8.5 | 81.7 ± 8.7 | 79.2 ± 8.3 | < 0.0001 |
Systolic blood pressure, mmHg | 122 ± 19.0 | 125 ± 19.2 | 121 ± 18.2 | 121 ± 19.4 | 120 ± 18.8 | 0.0002 |
Diastolic blood pressure, mmHg | 75.7 ± 12.8 | 78.1 ±13.1 | 76.0 ± 12.8 | 74.9 ± 12.4 | 73.9 ±12.4 | < 0.0001 |
γ-glutamyltransferase, IU/l | 26 (18-45) | 32 (22-55) | 28 (18-48) | 24 (17-40) | 23 (16-38) | < 0.0001 |
Amylase, IU/l (range) | 74.0 ± 23.6 (31-193) | 48.7 ± 6.3 (31-57) | 63.4 ± 3.5 (58-69) | 77.5 ± 4.8 (70-86) | 106 ± 19.1 (87-193) | -- |
Total cholesterol, mg/dl | 205 ± 33.9 | 205 ± 33.7 | 204 ± 33.9 | 205 ± 32.8 | 208 ± 35.3 | 0.18 |
Triglyceride, mg/dl | 94 (68-136) | 110 (75-159) | 95 (69-140) | 92 (66-132) | 85 (63-123) | < 0.0001 |
HDL-C, mg/dl | 61.0 ± 14.9 | 58.3 ± 14.2 | 59.9 ± 14.1 | 61.7 ± 15.4 | 63.9 ± 15.3 | < 0.0001 |
Fasting plasma glucose, mg/dl | 101 ± 18.1 | 104 ± 23.0 | 101 ± 18.3 | 99.8 ± 14.8 | 98.8 ± 14.6 | < 0.0001 |
HbA1c, % | 5.75 ± 0.61 | 5.81 ± 0.79 | 5.75 ± 0.65 | 5.71 ± 0.45 | 5.74 ± 0.51 | 0.02 |
CRP, mg/l | 0.53 (0.30-0.70) | 0.62 (0.30-1.15) | 0.51 (0.30-0.70) | 0.52 (0.30-0.80) | 0.47 (0.30-0.70) | < 0.0001 |
eGFR, ml/min/1.73 m2 | 76.0 ± 13.9 | 79.7 ± 13.2 | 77.7 ± 13.5 | 75.0 ± 13.3 | 72.0 ± 14.4 | < 0.0001 |
Metabolic syndrome, n (%) | 438 (18.1) | 155 (25.4) | 111 (19.0) | 105 (17.1) | 67 (10.9) | < 0.0001* |
Diabetes, n (%) | 201 (8.3) | 75 (12.3) | 47 (8.0) | 38 (6.2) | 41 (6.6) | 0.0004* |
Medical history of | Â | Â | Â | Â | Â | Â |
   Cardiovascular diseases, n (%) | 85 (3.5) | 19 (3.1) | 13 (2.2) | 26 (4.2) | 27 (4.4) | 0.14* |
   Stroke, n (%) | 41 (1.7) | 6 (1.0) | 5 (0.9) | 10 (1.6) | 20 (3.2) | 0.004* |
Medications for | Â | Â | Â | Â | Â | Â |
   Hypertension, n (%) | 413 (17.0) | 103 (16.9) | 98 (16.8) | 96 (15.7) | 116 (18.8) | 0.52* |
   Hypercholesterolemia, n (%) | 254 (10.5) | 61 (10.0) | 55 (9.4) | 51 (8.3) | 87 (14.1) | 0.006* |
   Diabetes, n (%) | 81 (3.3) | 23 (3.8) | 16 (2.7) | 18 (2.9) | 24 (3.9) | 0.59* |
Current smoker, n (%) | 629 (25.9) | 236 (38.7) | 177 (30.3) | 125 (20.4) | 91 (14.7) | < 0.0001* |
Daily alcohol consumption, n (%) | 757 (31.2) | 224 (36.7) | 203 (34.7) | 170 (27.7) | 160 (25.9) | < 0.0001* |
Infrequent exercise, n (%) | 1,650 (68.0) | 448 (73.4) | 405 (69.2) | 416 (67.9) | 381 (61.8) | 0.0002* |