Phenotype | Prevalence | Families | Lod Score | P-value | Empirical P-value |
---|
CAD
| 28.20% | 15 | 1.39 | 0.006 | 0.005 |
Stroke
| 14.80% | 5 | 1.04 | 0.014 | 0.002 |
Vasculopathy
| 53.80% | 48 | 0.64 | 0.040 | 0.053 |
Macrovascular Pathology
| 70.10% | 78 | 2.21 | 0.0007 | 0.002 |
- Prevalence = phenotype prevalence among the family subjects studied; Families = families number analyzed; Lod score = derived from the non-parametric linkage analysis by Merlin; Empirical P-value = derived from 1000 replicates by using the gene dropping method; CAD = coronary artery disease; Vasculopathy = based on the presence of plaques and/or angioplasty of carotid arteries, coronary arteries, lower extremities arteries; Macrovascular Pathology = based on the presence of CAD and/or Stroke/TIA and/or Vasculopathy.