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Table 4 Correlation between PAI-1 and tPA activities and antigens and tPA/PAI-1 complex parameters among normal group (n = 131)

From: Association of plasminogen activator inhibitor-1 and tissue plasminogen activator with type 2 diabetes and metabolic syndrome in Malaysian subjects

Parameters

Adjusted for

PAI-1 activity (IU/ml)

PAI-1 antigen (ng/ml)

tPA activity (U/ml)

tPA antigen (ng/ml)

tPA/PAI-1complex (ng/ml)

PAI-1 activity

Age, gender, race, BMI, HDL-c & HOMA (IR)

1

0.085(0.973)

0.051(0.276)

-0.100(0.598)

0.035(0.552)

PAI-1 antigen

Age, gender, race, HDL-c & HOMA (IR)

 

1

0.044(0.60)

0.111(0.642)

0.029(0.03)

tPA activity

Age, gender, race & FBS

  

1

-0.444(7.7 × 10-13)

-0.090(0.001)

tPA antigen

Age, gender, race & IS

   

1

0.202(3.5 × 10-7)

  1. Result presented as adjusted r2 (P-value) assessed by Linear regression. Bolt values are significant.