Table 2 Comparison of fibrinolytic PAI-1 and tPA between normal, non-diabetic metabolic syndrome, type 2 diabetes with and without metabolic syndrome and total type 2 diabetes groups

PAI-1 activity (IU/ml)

12.8(11.1-14.7)

28.7(25.1-32.8)

11.0(9.37-12.9)

29.0(26.1-32.1)

21.7(19.7-23.9)

p-value

^a 3.0 × 10 ^-15 , ^c 1.5 × 10 ^-18

^a0.167

^a 9.8 × 10 ^-19 , ^c 1.8 × 10 ^-21

^a 1.7 × 10 ^-8 , ^b 0.02

PAI-1 antigen (ng/ml)

30.2(27.1-33.7)

33.0(29.7-36.6)

18.2(16.2-20.6)

28.4(26.5-30.5)

25.4(23.9-27.1)

p-value

^a0.259

^a 2.2 × 10 ^-9 , ^b 6.9 × 10 ^-13

^b0.02, ^c5.1 × 10^-10

^a0.01, ^b4.7 × 10^-5

tPA activity (U/ml)

3.49(3.11-3.92)

3.51(3.14-3.91)

3.91(3.42-4.47)

2.82(2.58-3.07)

3.11(2.89-3.34)

p-value

^a0.965

^a0. 206

^a0.003, ^b0.002, ^c6.7 × 10^-5

^a0.03, ^b0.03

tPA antigen (ng/ml)

4.62(4.10-5.21)

5.99(5.35-6.70)

9.15(8.04-10.4)

9.85(9.14-10.6)

9.67(9.07-10.31)

p-value

^a 0.002

^a 1.3 × 10 ^-13 , ^b 1.3 × 10 ^-6

^a 8.9 × 10 ^-24 , ^b 1.3 × 10 ^-12

^a 3.0 × 10 ^-24 , ^b 1.7 × 10 ^-12

tPA/PAI-1 complex (ng/ml)

3.50(2.89-4.23)

3.57(2.97-4.30)

2.59(2.09-3.20)

3.91(3.46-4.42)

3.52(3.17-3.92)

p-value

^a0.879

^a0.04, ^b0.02

^a0.336, ^c0.001

^a0.94