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Table 1 Demography and Biochemical parameters among normal, non-diabetic metabolic syndrome and type 2 diabetes with and without metabolic syndrome groups

From: Association of plasminogen activator inhibitor-1 and tissue plasminogen activator with type 2 diabetes and metabolic syndrome in Malaysian subjects

Parameters

Normal (n = 131)

Non-diabetic MetS (n = 101)

Type 2 diabetes

    

without MetS (n = 76)

with MetS (n = 227)

Gender%

Male/Female

18.5/29.2

23.9/14.8

17.7/11.3

39.9/44.7

 

Malay

25.9

17.5

13.7

43.0

Races %

Chinese

36.1

22.1

14.8

27.0

 

Indian

12.1

18.8

14.8

54.4

Age (yrs)

 

47.2(44.9-49.7)

52.1(50.0-54.3)

49.8(47.6-52.1)

51.4(50.5-52.4)

 

p-value

 

a 0.003

a0.349

a 0.002

Body Mass Index (kg/m2)

 

22.7(22.1-23.3)

27.2(26.4-28.0)

23.34(22.5-24.3)

29.8(29.2-30.3)

 

p-value

 

a 3.8 × 10 -13

a0.515, b6.2 × 10-10

a 3.8 × 10 -13 , b 3.2 × 10 -6 , c 3.8 × 10 -13

Waist circumference (cm)

 

79.2(77.4-81.1)

94.5(92.8-96.3)

82.9(80.7-85.2)

98.6(97.4-99.7)

 

p-value

 

a 3.8 × 10 -13

a 0.02 , b 4.2 × 10 -13

a 3.8 × 10 -13 , b 0.006, c 3.8 × 10 -13

Diastolic Blood Pressure (mmHg)

 

80.0(78.4-81.5)

85.6(83.6-87.6)

79.3(77.1-81.5)

83.1(81.7-84.5)

 

p-value

 

a 1.7 × 10 -4

a0.966, b2.3 × 10-4

a0.02, b0.004, c0.02

Systolic Blood Pressure (mmHg)

 

130(127-134)

139(136-143)

129(125-134)

136(134-139)

 

p-value

 

a 0.002

a0.965, b0.002

a0.02, c0.02

Triglyceride (mmol/l)

 

1.08(1.00-1.17)

1.59(1.46-1.72)

1.38(1.19-1.57)

1.78(1.66-1.91)

 

p-value

 

a 1.6 × 10 -6

a 0.02

a 3.6 × 10 -13 , c 0.001

High Density Lipoprotein (mmol/l)

 

1.54(1.48-1.61)

1.26(1.20-1.31)

1.22(1.15-1.29)

1.15(1.11-1.18)

 

p-value

 

a 1.2 × 10 -10

a 2.6 × 10 -12

a 4.8 × 10 -13 , b 0.008

Fasting Blood Glucose (mmol/l)

 

5.02(4.93-5.10)

5.36(5.23-5.49)

8.05(7.41-8.74)

7.74(7.39-8.11)

 

p-value

 

0.24a

a 3.8 × 10 -13 , b 3.8 × 10 -13

a 3.8 × 10 -13 , b 3.8 × 10 -13

Insulin (pmol/l)

 

45.7(41.7-50.1)

77.3(69.6-85.8)

63.7(52.9-76.5)

120(110-131)

 

p-value

 

a 7.3 × 10 -9

a 0.002

a 4.1 × 10 -13 , b 5.0 × 10 -8 , c 1.4 × 10 -12

Insulin resistance (IR)

 

0.91(0.83-1.01)

1.53(1.37-1.69)

1.49(1.24-1.77)

2.59(2.38-2.81)

 

p-value

 

a 1.0 × 10 -6

a 3.2 × 10 -5

a 4.1 × 10 -13 , b 2.5 × 10 -12 , c 3.8 × 10 11

  1. The result presented as geometric mean and 95% confidence interval of mean, avs control group: bvs non-diabetic metabolic syndrome group: cvs type 2 diabetes without metabolic syndrome which evaluated by ANOVA. Bolt values are significant. MetS: metabolic syndrome.