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Table 1 Baseline characteristics of diabetic patients with (CAD) and without (Non-CAD) coronary artery disease, as defined by coronary angiography

From: Association of glycemic variability and the presence and severity of coronary artery disease in patients with type 2 diabetes

 

Non-CAD group (n = 92)

CAD group (n = 252)

p value

Male (%)

48 (52.2)

165 (65.5)

0.025

Age (years)

61 ± 9

65 ± 9

< 0.001

Cigarette smoking (%)

19 (20.7)

91 (36.1)

0.007

Hypertension (%)

56 (60.9)

177 (70.2)

NS

Blood pressure

   

   Systolic (mmHg)

123 ± 17

126 ± 20

NS

   Diastolic (mmHg)

76 ± 8

78 ± 9

NS

Hyperlipidemia (%)

48 (52.2)

154 (61.1)

NS

Duration of diabetes (months)

58 ± 68

78 ± 77

0.022

Oral anti-hyperglycemic therapy (%)

42 (45.7)

111 (44.0)

NS

Insulin (%)

33 (35.9)

103 (40.9)

NS

Statins (%)

57 (61.9)

175 (69.4)

NS

Cholesterol

   

   Total cholesterol (mmol/L)

4.6 ± 1.1

4.8 ± 1.2

NS

   LDL-C (mmol/L)

2.7 ± 0.8

2.9 ± 1.0

NS

   HDL-C (mmol/L)

1.0 ± 0.2

1.1 ± 0.3

NS

Triglycerides (mmol/L)

2.1 ± 1.2

2.2 ± 1.6

NS

Creatinine (μmol/L)

77 ± 19

87 ± 23

< 0.001

eGFR (ml/min/1.73 m2)

87 ± 23

79 ± 18

< 0.001

Fasting plasma glucose (mmol/L)

7.3 ± 1.8

7.6 ± 2.4

NS

Hemoglobin A1c (%)

7.5 ± 1.4

7.6 ± 1.5

NS

MAGE (mmol/L)

3.2 ± 1.2

3.7 ± 1.4

< 0.001

MODD (mmol/L)

2.4 ± 1.0

2.5 ± 1.0

NS

PPGE (mmol/L)

3.6 ± 1.4

3.9 ± 1.6

0.036

BMI (kg/m2)

26.0 ± 2.2

26.4 ± 2.4

NS

hs-CRP (mg/L)

5.8 ± 6.7

10.7 ± 12.4

< 0.001

  1. Abbreviations: CAD, coronary artery disease; LDL-C, lower-density lipoprotein-cholesterol; HDL-C, high-density lipoprotein-cholesterol; eGFR, estimated glomerular filtration rate; MAGE, the mean amplitude of glycemic excursions; MODD, the mean of daily differences; PPGE, postprandial blood glucose excursions; BMI, body mass index; hs-CRP, highsensitive-C reactive protein.
  2. Data are mean ± SD and number (%).