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Table 5 Association between the DDAH1 gene polymorphism and plasma ADMA levels, L-arginine levels and L-arginine/ADMA ratio

From: The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study

SNP ID Genotype ADMA μmol/l mean (95% CI) L-arginine μmol/l mean (95% CI) L-arginine/ADMA mean (95% CI)
rs233112     
  AA 0.45 (0.43-0.46)* 95.8 (91.7-99.9) 222.5 (212.0-233.0)
  AG 0.45 (0.44-0.46) 92.4 (89.2-95.5) 210.7 (202.9-218.5)
  GG 0.47 (0.46-0.49) 95.1 (91.7-96.2) 209.3 (208.5-219.6)
rs1498374     
  GG 0.45 (0.44-0.46)* 93.8 (91.1-96.5) 216.2 (209.5-222.9)
  GA 0.46 (0.45-0.47) 94.0 (89.8-98.2) 210.5 (200.0-220.9)
  AA 0.51 (0.46-0.57) 94.7 (81.5-107.9) 214.0 (208.4-219.5)
rs1498373     
  CC 0.44 (0.43-0.45) *** 94.0 (90.6-97.3) 219.5 (211.0-227.9)
  CT 0.46 (0.45-0.47) 93.3 (90.0-96.5) 210.4 (202.2-218.7)
  TT 0.49 (0.46-0.52) 96.8 (89.2-104.5) 204.0 (187.7-219.6)
rs1241321     
  GG 0.45 (0.43-0.47) 94.8 (88.5-101.0) 220.1(203.5-236.6)
  GA 0.45 (0.44-0.46) 94.2 (90.9-97.5) 215.1 (207.0-223.2)
  AA 0.46 (0.45-0.47) 93.1 (89.7-96.6) 210.3 (201.8-218.8)
rs1403956     
  GG 0.45 (0.44-0.46)* 98.0 (91.1-96.9) 217.6 (210.2-224.9)
  GA 0.46 (0.45-0.47) 93.2 (89.4-96.9) 209.4 (200.3-218.5 )
  AA 0.49 (0.46-0.52) 98.7 (88.4-109.1) 203.3 (182.1-224.6)
rs587843     
  CC 0.46 (0.44-0.48) 92.3 (86.5-98.0) 207.7 (193.6-221.7)
  CG 0.45 (0.44-0.46) 94.3 (91.2-97.2) 216.7 (209.3-224.3)
  GG 0.46 (0.45-0.47) 94.2 (90.2-98.3) 212.8 (202.7-223.0)
  1. *: p < 0.05, ***: p < 0.001, compared by one-way analysis of variance test.