Table 2 Association between the DDAH1 gene polymorphisms and type 2 diabetes
SNP ID | Genotype | Type 2 DM patients, n (%) | Non-DM subjects, n (%) | Multivariate adjusted OR* (95% CI), p value |
|---|---|---|---|---|
rs233112 | Â | Â | Â | Â |
| Â | AA | 98 (31.8) | 149 (29.6) | Â |
| Â | AG | 153 (49.7) | 256 (50.9) | 0.99 (0.78-1.19) |
| Â | GG | 57 (18.5) | 98 (19.5) | 0.72 |
rs1498374 | Â | Â | Â | Â |
| Â | GG | 217 (70.2) | 347 (69.0) | Â |
| Â | AG | 85 (27.5) | 146 (29.0) | 0.99 (0.74-1.32) |
| Â | AA | 7 (2.3) | 10 (2.0) | 0.94 |
rs1498373 | Â | Â | Â | Â |
| Â | CC | 138 (44.8) | 237 (46.9) | Â |
| Â | CT | 137 (44.5) | 231 (45.7) | 1.21 (0.96-1.52) |
| Â | TT | 33 (10.7) | 37 (7.3) | 0.11 |
rs1241321 | Â | Â | Â | Â |
| Â | GG | 49 (15.9) | 66 (13.1) | Â |
| Â | AG | 160 (51.8) | 225 (44.6) | 0.75 (0.60-0.93) |
| Â | AA | 100 (32.4) | 214 (42.4) | 0.008 ** |
rs1403956 | Â | Â | Â | Â |
| Â | GG | 180 (58.3) | 295 (58.5) | Â |
| Â | AG | 118 (38.2) | 185 (36.7) | 0.99 (0.77-1.27) |
| Â | AA | 11 (3.6) | 24 (4.8) | 0.92 |
rs587843 | Â | Â | Â | Â |
| Â | CC | 46 (14.9) | 87 (17.3) | Â |
| Â | CG | 169 (54.7) | 239 (47.5) | 0.93 (0.75-1.15) |
| Â | GG | 94 (30.4) | 177 (35.2) | 0.51 |