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Table 2 Association between the DDAH1 gene polymorphisms and type 2 diabetes

From: The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study

SNP ID Genotype Type 2 DM patients, n (%) Non-DM subjects, n (%) Multivariate adjusted OR* (95% CI), p value
rs233112     
  AA 98 (31.8) 149 (29.6)  
  AG 153 (49.7) 256 (50.9) 0.99 (0.78-1.19)
  GG 57 (18.5) 98 (19.5) 0.72
rs1498374     
  GG 217 (70.2) 347 (69.0)  
  AG 85 (27.5) 146 (29.0) 0.99 (0.74-1.32)
  AA 7 (2.3) 10 (2.0) 0.94
rs1498373     
  CC 138 (44.8) 237 (46.9)  
  CT 137 (44.5) 231 (45.7) 1.21 (0.96-1.52)
  TT 33 (10.7) 37 (7.3) 0.11
rs1241321     
  GG 49 (15.9) 66 (13.1)  
  AG 160 (51.8) 225 (44.6) 0.75 (0.60-0.93)
  AA 100 (32.4) 214 (42.4) 0.008 **
rs1403956     
  GG 180 (58.3) 295 (58.5)  
  AG 118 (38.2) 185 (36.7) 0.99 (0.77-1.27)
  AA 11 (3.6) 24 (4.8) 0.92
rs587843     
  CC 46 (14.9) 87 (17.3)  
  CG 169 (54.7) 239 (47.5) 0.93 (0.75-1.15)
  GG 94 (30.4) 177 (35.2) 0.51
  1. * Odds ratio (OR) for rs233112: A versus G; rs1498374: A versus G; rs1498373: T versus C; rs1241321 A versus G; rs1403956 A versus G; rs587843: G versus C.
  2. ** adjusted for multiple comparison: p = 0.048; AA vs GG +AG: OR (95% CI) = 0.64 (0.47-0.87), p = 0.004.