Pancreatic islet surface areas of B6.apoE-/- and BALB.apoE-/- mice fed a chow or Western diet. Cryosections of the pancreas were stained with haematoxylin and eosin. The surface area of all pancreatic islets from sections spaced approximately at 500 μm was measured for each mouse. Values are means ± SE of 3 to 10 mice. * P < 0.05 vs. B6 mice.