Glucose tolerance test (GTT) and insulin tolerance test (ITT) for B6.apoE-/- and BALB.apoE-/- mice fed a Western diet. For GTT, overnight fasted mice were subject to an intraperitoneal injection of glucose (1 g/kg). ITT was performed by an intraperitoneal injection of insulin (0.75 U/kg) to non-fasted mice. Blood glucose concentrations were determined with a glucometer using blood taken from cut tail tips at the indicated time points. Values are means ± SE of 4 or 5 mice. * P < 0.05 vs. B6 mice.