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Table 1 Clinical characteristics of patients with DM and Controls

From: Impact of glycemic control on circulating endothelial progenitor cells and arterial stiffness in patients with type 2 diabetes mellitus

 

DM patients

n = 234

Controls

n = 121

P-value

Age, years

56.5 ± 7.6

56.5 ± 8.4

0.99

Males, n (%)

119 (51)

59 (49)

0.74

Hypertension, n (%)

96 (41)

18 (15)

< 0.01

Hypercholesterolemia, n (%)

114 (49)

24 (20)

< 0.01

Ever-smokers, n (%)

72 (31)

7 (6)

< 0.01

Duration of DM, yrs

10.0 ± 8.0

-

 

Body-mass index, kg/m2

25.1 ± 4.7

21.5 ± 3.2

< 0.01

Waist-hip circumference ratio

0.9 ± 0.1

0.8 ± 0.1

< 0.01

Body weight, kg

64.6 ± 10.6

56.4 ± 9.1

< 0.01

Systolic blood pressure, mmHg

144.2 ± 21.2

118.8 ± 22.9

< 0.01

Diastolic blood pressure, mmHg

79.6 ± 8.8

72.3 ± 8.2

< 0.01

Fasting blood glucose, mmol/L

7.2 ± 2.2

4.9 ± 0.5

< 0.01

HbA1c, %

7.7 ± 1.5

5.8 ± 0.3

< 0.01

Triglyceride, mmol/L

1.6 ± 1.2

1.3 ± 0.9

< 0.01

Total cholesterol, mmol/L

4.6 ± 0.9

5.1 ± 0.8

< 0.01

LDL-C, mmol/L

2.6 ± 0.8

2.9 ± 0.7

< 0.01

HDL-C, mmol/L

1.3 ± 0.4

1.6 ± 0.4

< 0.01

Creatinine, μmol/L

84.6 ± 27.2

71.0 ± 16.6

< 0.01

GFR, ml/min/1.73m2

55.4 ± 15.3

60.0 ± 13.7

< 0.01

Beta-blocker, n (%)

106 (45%)

10 (8%)

< 0.01

Calcium channel blocker, n (%)

77 (33%)

3 (2%)

< 0.01

ACEI/ARB, n (%)

122 (52%)

6 (5%)

< 0.01

Aspirin, n (%)

103 (44%)

9 (7%)

< 0.01

Statin, n (%)

119 (51%)

9 (7%)

< 0.01

Insulin, n (%)

35 (15%)

0 (0%)

< 0.01

Log CD34/KDR+ EPCs, 10-3/ml

0.96 ± 0.31

1.23 ± 0.36

< 0.01

Log CD133/KDR+ EPCs, 10-3/ml

0.70 ± 0.26

1.13 ± 0.38

< 0.01

Log baPWV, cm/s

3.24 ± 0.08

3.18 ± 0.09

< 0.01

  1. Abbreviations: T2DM = Type 2 diabetes mellitus; HbA1c = hemoglobin A1c; LDL-C = low-density lipoprotein cholesterol; HDL-C = high-density lipoprotein cholesterol; GFR = glomerular filtration rate; ACEI = angiotensin converting enzyme inhibitor; ARB = angiotensin receptor blocker; EPC = endothelial progenitor cell; baPWV = brachial-ankle pulse wave velocity