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Table 1 Clinical characteristics of patients with DM and Controls

From: Impact of glycemic control on circulating endothelial progenitor cells and arterial stiffness in patients with type 2 diabetes mellitus

  DM patients
n = 234
Controls
n = 121
P-value
Age, years 56.5 ± 7.6 56.5 ± 8.4 0.99
Males, n (%) 119 (51) 59 (49) 0.74
Hypertension, n (%) 96 (41) 18 (15) < 0.01
Hypercholesterolemia, n (%) 114 (49) 24 (20) < 0.01
Ever-smokers, n (%) 72 (31) 7 (6) < 0.01
Duration of DM, yrs 10.0 ± 8.0 -  
Body-mass index, kg/m2 25.1 ± 4.7 21.5 ± 3.2 < 0.01
Waist-hip circumference ratio 0.9 ± 0.1 0.8 ± 0.1 < 0.01
Body weight, kg 64.6 ± 10.6 56.4 ± 9.1 < 0.01
Systolic blood pressure, mmHg 144.2 ± 21.2 118.8 ± 22.9 < 0.01
Diastolic blood pressure, mmHg 79.6 ± 8.8 72.3 ± 8.2 < 0.01
Fasting blood glucose, mmol/L 7.2 ± 2.2 4.9 ± 0.5 < 0.01
HbA1c, % 7.7 ± 1.5 5.8 ± 0.3 < 0.01
Triglyceride, mmol/L 1.6 ± 1.2 1.3 ± 0.9 < 0.01
Total cholesterol, mmol/L 4.6 ± 0.9 5.1 ± 0.8 < 0.01
LDL-C, mmol/L 2.6 ± 0.8 2.9 ± 0.7 < 0.01
HDL-C, mmol/L 1.3 ± 0.4 1.6 ± 0.4 < 0.01
Creatinine, μmol/L 84.6 ± 27.2 71.0 ± 16.6 < 0.01
GFR, ml/min/1.73m2 55.4 ± 15.3 60.0 ± 13.7 < 0.01
Beta-blocker, n (%) 106 (45%) 10 (8%) < 0.01
Calcium channel blocker, n (%) 77 (33%) 3 (2%) < 0.01
ACEI/ARB, n (%) 122 (52%) 6 (5%) < 0.01
Aspirin, n (%) 103 (44%) 9 (7%) < 0.01
Statin, n (%) 119 (51%) 9 (7%) < 0.01
Insulin, n (%) 35 (15%) 0 (0%) < 0.01
Log CD34/KDR+ EPCs, 10-3/ml 0.96 ± 0.31 1.23 ± 0.36 < 0.01
Log CD133/KDR+ EPCs, 10-3/ml 0.70 ± 0.26 1.13 ± 0.38 < 0.01
Log baPWV, cm/s 3.24 ± 0.08 3.18 ± 0.09 < 0.01
  1. Abbreviations: T2DM = Type 2 diabetes mellitus; HbA1c = hemoglobin A1c; LDL-C = low-density lipoprotein cholesterol; HDL-C = high-density lipoprotein cholesterol; GFR = glomerular filtration rate; ACEI = angiotensin converting enzyme inhibitor; ARB = angiotensin receptor blocker; EPC = endothelial progenitor cell; baPWV = brachial-ankle pulse wave velocity