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Table 4 Serum levels of IL-18 and IL-18 BP in relation to CAD subgroups

From: Circulating levels of IL-18 are significantly influenced by the IL-18 +183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an Observational Study

Disease Entities

IL 18 pg/mL*

p-value †

IL 18 BP pg/mL*

p-value †

MI

+

252 (197, 327)

> 0.2

23.5 (19.4, 28.5)

0.191

 

-

245 (194, 320)

 

23.0 (19.2, 28.2)

 

HT

+

248 (198, 318)

> 0.2

23.5 (19.5, 29.1)

0.066

 

-

248 (190, 327)

 

22.8 (18.9, 27.2)

 

T2DM

+

259 (207, 364)

0.001

23.6 (19.6, 29.0)

0.163

 

-

244 (192, 311)

 

23.0 (19.2, 28.1)

 

MetS

+

265 (217, 356)

< 0.0001

24.1 (19.8, 29.3)

0.010

 

-

243 (188, 310)

 

22.8 (19.1, 28.0)

 

Men

 

256 (203, 329)

< 0.0001

23.2 (19.3, 28.3)

> 0.2

Women

 

221 (176, 290)

 

23.1 (18.9, 28.1)

 

Current Smokers

+

252 (207, 323)

> 0.2

23.0 (19.2, 27.1)

> 0.2

 

-

247 (194, 323)

 

23.2 (19.3, 28.7)

 
  1. * Median levels (25- and 75 percentiles)
  2. † Mann-Whitney test