Table 2 Frequencies of the IL-18 polymorphisms in CAD patients and controls
IL-18 Genotype | CAD (%) | Controls (%) | p-value * | |
|---|---|---|---|---|
+183 A/G | AA | 543 (55) | 114 (56) | |
AG | 391 (39) | 85 (42) | ||
GG | 62 (6) | 5 (2) | ||
G-allele frequency | 0.259 | 0.234 | > 0.2 | |
-137 G/C | GG | 532 (53) | 108 (53) | |
GC | 394 (40) | 82 (40) | ||
CC | 69 (7) | 14 (7) | ||
C-allele frequency | 0.267 | 0.270 | > 0.2 | |
-607 C/A | CC | 364 (37) | 74 (36) | |
CA | 500 (50) | 96 (47) | ||
AA | 132 (13) | 34 (17) | ||
A-allele frequency | 0.384 | 0.403 | > 0.2 | |