| Normal glucose tolerance | Type 2 diabetes | Type 2 diabetes | P-value | |||
---|---|---|---|---|---|---|---|
 |  |  | without carotid plaque | with carotid plaque |  | ||
 | (N = 30) | (N = 30) | (N = 30) |  | |||
Age (years) | 54.07 | ± 8.14 | 53.1 | ± 6.81 | 56.47 | ± 6.04 | 0.169 |
Gender (M:F) | 12 | : 18 | 10 | : 20 | 15 | : 15 | 0.418 |
BMI (kg/m2) | 23.99 | ± 2.88 | 23.89 | ± 2.29 | 24.18 | ± 2.11 | 0.895 |
Waist circumference (cm) | 85.19 | ± 6.05a | 93.68 | ± 6.76b | 95.12 | ± 3.98 b | < 0.001 |
SBP (mmHg) | 119.67 | ± 12.73 a | 119.33 | ± 10.56 a | 129.83 | ± 17.95 b | 0.007 |
DBP (mmHg) | 77.67 | ± 10.06 | 74.5 | ± 8.55 | 77.72 | ± 9.92 | 0.332 |
Fasting blood glucose (mmol/L) | 5.16 | ± 0.55 a | 7.06 | ± 2.06 b | 7.28 | ± 1.53 b | < 0.001 |
HOMA_IR | 1.66 | (0.92, 2.52) a | 2.7 | (1.91, 4.10) b | 2.96 | (1.92, 3.86) b | 0.002 |
HbA1c | 5.68 | ± 0.34 a | 7.27 | ± 1.04 b | 7.4 | ± 0.94 b | < 0.001 |
LDL cholesterol (mmol/L) | 2.58 | ± 0.81 | 2.28 | ± 0.60 | 2.27 | ± 0.50 | 0.122 |
HDL cholesterol (mmol/L) | 1.41 | ± 0.39 | 1.24 | ± 0.34 | 1.29 | ± 0.27 | 0.159 |
Triglyceride (mmol/L) | 1.02 | (0.70, 1.56) | 1.17 | (0.98, 2.29) | 1.36 | (1.02, 1.68) | 0.057 |
hsCRP (mg/dL) | 0.56 | (0.34, 1.45) | 0.57 | (0.35, 1.21) | 0.45 | (0.30, 1.13) | 0.428 |
Carotid IMT (cm) | 0.84 | ± 0.11 a | 0.86 | ± 0.12 a | 0.98 | ± 0.16 b | < 0.001 |
baPWV (m/sec) | 13.26 | ± 1.77 a | 14.29 | ± 2.57 a | 16.22 | ± 3.07 b | < 0.001 |
Current smoker (%) | 26.77 | 30 | 46.67 | 0.218 | |||
Statin (%) | 10.00 a | 33.33 ab | 40.44 b | 0.024 | |||
Anti-platelet agent (%) | 6.67 | 6.67 | 26.67 | 0.031 | |||
ARB or ACE inhibitor (%) | 10.00 a | 16.67 ab | 40.00 b | 0.013 | |||
Calcium channel blocker (%) | 10 | 13.33 | 20 | 0.533 | |||
Insulin (%) | - | 13.33 | 16.66 | 0.718 | |||
Sulfonylurea (%) | - | 33.33 | 43.33 | 0.426 | |||
Glucophage (%) | - | 53.33 | 56.66 | 0.795 | |||
Thiazolidinedione (%) | - | 10 | 13.33 | 0.688 | |||
Duration of diabetes (years) | - | 8.47 | ± 5.46 | 12.17 | ± 7.35 | < 0.001 |