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Table 1 Baseline characteristics of study subjects

From: Association of circulating omentin-1 level with arterial stiffness and carotid plaque in type 2 diabetes

 

Normal glucose tolerance

Type 2 diabetes

Type 2 diabetes

P-value

   

without carotid plaque

with carotid plaque

 
 

(N = 30)

(N = 30)

(N = 30)

 

Age (years)

54.07

± 8.14

53.1

± 6.81

56.47

± 6.04

0.169

Gender (M:F)

12

: 18

10

: 20

15

: 15

0.418

BMI (kg/m2)

23.99

± 2.88

23.89

± 2.29

24.18

± 2.11

0.895

Waist circumference (cm)

85.19

± 6.05a

93.68

± 6.76b

95.12

± 3.98 b

< 0.001

SBP (mmHg)

119.67

± 12.73 a

119.33

± 10.56 a

129.83

± 17.95 b

0.007

DBP (mmHg)

77.67

± 10.06

74.5

± 8.55

77.72

± 9.92

0.332

Fasting blood glucose (mmol/L)

5.16

± 0.55 a

7.06

± 2.06 b

7.28

± 1.53 b

< 0.001

HOMA_IR

1.66

(0.92, 2.52) a

2.7

(1.91, 4.10) b

2.96

(1.92, 3.86) b

0.002

HbA1c

5.68

± 0.34 a

7.27

± 1.04 b

7.4

± 0.94 b

< 0.001

LDL cholesterol (mmol/L)

2.58

± 0.81

2.28

± 0.60

2.27

± 0.50

0.122

HDL cholesterol (mmol/L)

1.41

± 0.39

1.24

± 0.34

1.29

± 0.27

0.159

Triglyceride (mmol/L)

1.02

(0.70, 1.56)

1.17

(0.98, 2.29)

1.36

(1.02, 1.68)

0.057

hsCRP (mg/dL)

0.56

(0.34, 1.45)

0.57

(0.35, 1.21)

0.45

(0.30, 1.13)

0.428

Carotid IMT (cm)

0.84

± 0.11 a

0.86

± 0.12 a

0.98

± 0.16 b

< 0.001

baPWV (m/sec)

13.26

± 1.77 a

14.29

± 2.57 a

16.22

± 3.07 b

< 0.001

Current smoker (%)

26.77

30

46.67

0.218

Statin (%)

10.00 a

33.33 ab

40.44 b

0.024

Anti-platelet agent (%)

6.67

6.67

26.67

0.031

ARB or ACE inhibitor (%)

10.00 a

16.67 ab

40.00 b

0.013

Calcium channel blocker (%)

10

13.33

20

0.533

Insulin (%)

-

13.33

16.66

0.718

Sulfonylurea (%)

-

33.33

43.33

0.426

Glucophage (%)

-

53.33

56.66

0.795

Thiazolidinedione (%)

-

10

13.33

0.688

Duration of diabetes (years)

-

8.47

± 5.46

12.17

± 7.35

< 0.001

  1. Data are expressed as the mean with SD, median (inter-quartile range), or percentage. P-value for overall difference among the groups was calculated from the analysis of variance (ANOVA), the Kruskal-Wallis H test, or Pearson's chi-square test. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HOMA-IR, homeostasis model assessment of insulin resistance; LDL, low-density lipoprotein; HDL, high-density lipoproteins; hsCRP, high sensitivity C-reactive protein; IMT, intima-media thickness; baPWV, brachial ankle pulse wave velocity; ARB, angiotensin receptor blocker; ACE, angiotensin-converting enzyme inhibitor.
  2. a, b, c: same letter indicates no statistical difference between the groups based on post hoc analysis.