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Table 3 Comparison of mean value of sST2, BNP and hs-CRP between the 4 study groups

From: Toll/Interleukin-1 receptor member ST2 exhibits higher soluble levels in type 2 diabetes, especially when accompanied with left ventricular diastolic dysfunction

Comparison

p-value

 

sST2

BNP

hs-CRP

A vs B

0,514

0,628

0,872

A vs C

0,007

0,213

0,004

A vs D

<0,001

0,207

0,017

B vs C

0,121

0,863

0,041

B vs D

<0,001

0,504

0,048

C vs D

0,001

0,091

0,659

Overall

<0,001

0,301

0,039

  1. Soluble ST2 was significantly different between group A (healthy controls) and patients with type 2 diabetes without (group C) LVDD (p = 0.007). Moreover, patients with type 2 diabetes with LVDD (group D) had the highest mean serum level of sST2 compared to the correspondent of the rest 3 subject groups: group A (p < 0.001), group B (p < 0.001) and group C (p = 0.001). The respective mean values of BNP for the 4 study groups could not achieve statistical difference. All subjects with type 2 diabetes presented higher hs-CRP levels compared to the non-diabetic population of the study.