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Table 3 Comparison of mean value of sST2, BNP and hs-CRP between the 4 study groups

From: Toll/Interleukin-1 receptor member ST2 exhibits higher soluble levels in type 2 diabetes, especially when accompanied with left ventricular diastolic dysfunction

Comparison p-value
  sST2 BNP hs-CRP
A vs B 0,514 0,628 0,872
A vs C 0,007 0,213 0,004
A vs D <0,001 0,207 0,017
B vs C 0,121 0,863 0,041
B vs D <0,001 0,504 0,048
C vs D 0,001 0,091 0,659
Overall <0,001 0,301 0,039
  1. Soluble ST2 was significantly different between group A (healthy controls) and patients with type 2 diabetes without (group C) LVDD (p = 0.007). Moreover, patients with type 2 diabetes with LVDD (group D) had the highest mean serum level of sST2 compared to the correspondent of the rest 3 subject groups: group A (p < 0.001), group B (p < 0.001) and group C (p = 0.001). The respective mean values of BNP for the 4 study groups could not achieve statistical difference. All subjects with type 2 diabetes presented higher hs-CRP levels compared to the non-diabetic population of the study.