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Table 1 Definition of study outcome events

From: Insulin resistance increases the occurrence of new cardiovascular events in patients with manifest arterial disease without known diabetes. The SMART study

Stroke Definite: relevant clinical features causing an increase in impairment of at least one grade on the modified Rankin scale, accompanied by an infarction on repeat brain imaging.
Probable: clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale; without documentation by means of brain imaging.
Myocardial infarction At least two of the following criteria:
(I) chest pain for at least 20 min, not disappearing after administration of nitrates;
(II) ST-elevation > 1 mm in two following leads or a left bundle branch block on the electrocardiogram;
(III) Creatinine kinase (CK) elevation of at least two times the normal value of CK and a myocardial band-fraction > 5% of the total CK.
Vascular mortality Death from ischemic or hemorrhagic stroke, congestive heart failure, myocardial infarction or rupture of abdominal aortic aneurysm.
Sudden death: unexpected cardiac death occurring within 1 hour after onset of symptoms, or within 24 hours given convincing circumstantial evidence.
Vascular death from other causes
Composite vascular outcome event A composite of stroke, myocardial infarction and vascular mortality completed with a probable or definite retinal infarction or bleeding and probable or definite hemorrhagic stroke.
All-cause mortality Death from any cause