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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Vasculoprotective effects of rosiglitazone through modulating renin-angiotensin system in vivo and vitro

Figure 3

Immunohistochemical staining of protein expression of angiotensin II type 1 receptor (AT 1 R) and angiotensin II type 2 receptor (AT 2 R) in aortic tissues. A and F: the negative controls of AT1R and AT2R for the immunohistochemistry, respectively, showing no positive staining. B and G: the regular diet group; C and H: the cholesterol-rich diet plus methylthiouracil (80 mg/Kg/day) group; D and I: group with cholesterol-rich diet plus methylthiouracil and rosiglitazone treatment. Rosiglitazone treatment markedly attenuated AT1R immunoreactivity induced by the cholesterol-rich diet plus methylthiouracil (D), while increased AT2R immunoreactivity (I). (Magnification: 400×).

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Cardiovascular Diabetology

ISSN: 1475-2840