Silent coronary artery disease in type 2 diabetes mellitus: the role of Lipoprotein(a), homocysteine and apo(a) polymorphism

Table 3 Results of a multiple logistic regression analysis with the presence of asymptomatic CAD as the dependent variable in diabetic patients

PREDICTORS	Odds Ratio	95% Confidence Intervals	p-value
MODEL 1
Microalbuminuria	7.09	2.65–18.96	<0.001
Smoking	2.72	1.17–5.85	<0.02
High Lp(a) levels	2.62	1.01–6.79	<0.05
Low HDL	2.39	1.06–5.38	<0.05
High tHcy levels	2.04	1.03–4.06	<0.05
MODEL 2
Apo(a) phenotypes	8.65	3.05–24.55	<0.001
Microalbuminuria	6.16	2.21–17.18	<0.01
Low HDL	3.16	1.28–7.81	<0.05
Smoking	2.53	1.05–6.08	<0.05
High tHcy levels	2.25	1.14–4.43	<0.05

Model 1, potential predictors: hypertension, family history of CAD, smoking, microalbuminuria, HbA1c, BMI, Lp(a), tHcy, cholesterol, triglycerides, LDL, HDL. Model 2, potential predictors: hypertension, family history of CAD, smoking, microalbuminuria, HbA1c, BMI, Lp(a), tHcy, cholesterol, triglycerides, LDL, HDL, Apo(a) phenotypes.

ISSN: 1475-2840