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Table 2 Characteristics of diabetic patients with asymptomatic CAD and without CAD.

From: Silent coronary artery disease in type 2 diabetes mellitus: the role of Lipoprotein(a), homocysteine and apo(a) polymorphism

  CAD NO CAD p-value
Number 75 75  
Sex (M/F) 62/13 62/13 NS
Age (years) 56.6 ± 6.2 56.7 ± 6.2 NS
Duration of diabetes (years) 7.9 ± 5.7 8.0 ± 4.9 NS
BMI 26.4 ± 3.4 26.1 ± 3.7 NS
HbA1c (%) 7.8 ± 1.4 7.4 ± 1.4 NS
Cholesterol (mmol/l)    
   Mean 5.6 ± 0.9 5.4 ± 1.0 NS
   Median 5.6 5.2  
   Range 3.8–9.0 3.4–8.6  
LDL (mmol/l)    
   Mean 2.7 ± 1.0 2.5 ± 1.0 NS
   Median 2.8 2.6  
   Range 1.0–5.9 0.5–6.0  
HDL (mmol/l)    
   Mean 1.1 ± 0.2 1.2 ± 0.2 <0.05
   Median 1.1 1.3  
   Range 0.6–2.0 0.9–2.1  
Triglycerides (mmol/l)    
   Mean 1.7 ± 0.6 1.6 ± 0.6 NS
   Median 1.7 1.5  
   Range 0.8–3.2 0.6–3.7  
Microalbuminuria (%) 42.7 10.7 <0.0001
AER (mg/day)    
   Mean 53.0 ± 67.8 22.5 ± 37.5 <0.01
   Median 25.0 10.0  
   Range 4.5–293.1 4.9–258.3  
Smokers (%) 57.3 29.3 <0.001
Family history of CAD (%) 36.0 30.7 NS
Hypertension (%) 53.3 57.3 NS
Autonomic neuropathy (%) 29.3 22.7 NS
Lp(a) levels (mg/dl)    
   Mean 22.0 ± 18.9 16.0 ± 19.4 <0.05
   Median 18.0 7.0  
   Range 0.5–85 0–88.5  
Subjects with Lp(a) levels >30 mg/dl (%) 33.3% 17.3% <0.05
tHcy levels (mmol/l)    
   Mean 13.6 ± 6.0 11.4 ± 4.9 <0.05
   Median 12.0 10.0  
   Range 7.4–41.1 5.1–35.6  
Subjects with tHcy levels >14.0 mmol/l (%) 42.7 26.7 <0.05
Subjects with at least one isoform of low MW (%) 70.7 29.3 <0.0001
  1. LDL = Low Density Lipoprotein; HDL = High Density Lipoprotein; BMI = Body Mass Index; AER = Albumin Excretion Rate. Lp(a) = Lipoprotein(a); tHcy = total homocysteine; Apo(a) = Apolipoprotein(a); CAD = Coronary Artery Disease; tHcy = total homocysteine; MW = Molecular Weight