Gender differences in factors influencing insulin resistance in elderly hyperlipemic non-diabetic subjects

Table 2 Detailed characteristics of the subjects under study

	MEN			WOMEN
	Controls N = 10 Mean ± SD	Hyperlipemic patients N = 20 Mean ± SD	p	Controls N = 20 Mean ± SD	Hyperlipemic patients N = 20 Mean ± SD	p
BMI	25.91 ± 3.58	28.51 ± 2.60	0.030	25.36 ± 3.72	26.73 ± 3.59	0.24
HOMA IR	1.685 ± 0.771	3.137 ± 1.419	0.002 _KS	1.717 ± 0.893	2.694 ± 1.011	0.001 _KS
QUICKI	0,3596 ± 0,0263	0,3266 ± 0,0185	0,002	0,3603 ± 0,0281	0,3332 ± 0,0192	0,0007
Uric acid (mmol/l)	270.5 ± 65.4	379.9 ± 84.2	0.003	236.1 ± 67.0	270.8 ± 58.9***	0.13
Glycemia (mmol/l)	5.31 ± 0.53	6.11 ± 0.95	0.029 _KS	5.26 ± 0.42	5.85 ± 0.70	0.0027
Insulin (mIU/l)	6.96 ± 2.80	11.43 ± 4.50	0.016 _KS	7.33 ± 3.80	10.27 ± 3.52	0.034 _KS
Proinsulin intact (pmol/l)	2.68 ± 1.15	5.51 ± 2.75	0.012 _KS	2.51 ± 1.76	4.49 ± 3.11	0.034 _KS
C-peptide (nmol/l)	0.66 ± 0.31	1.11 ± 0.39	0.0148	0.75 ± 0.35	0.92 ± 0.34	0.22_KS
Leptin (ng/ml)	3.07 ± 3.38	6.21 ± 3.78	0.012 _KS	16.06 ± 13***	17.79 ± 5.9**	0.17_KS
TNFα (pg/ml)	14.2 ± 4.15	11.52 ± 2.77	0.063_KS	11.65 ± 6.80	12.73 ± 9.15	0.43_KS
hFABP (pg/ml)	3.86 ± 2.47	4.53 ± 1.97	0.46	3.09 ± 1.80	3.79 ± 2.00	0.41_KS
ACL-IgG (IU/ml)	13.08 ± 6.75	19.63 ± 16.9	0.57_KS	12.28 ± 6.38	16.35 ± 16.8	0.99_KS

BMI = body mass index, HOMA IR and QUICKI = homeostatic indexes of insulin resistance (see Methods), TNFα = tumor necrosis factor α, hFABP = heart fraction of fatty acid binding protein, ACL-IgG = IgG anticardiolipin. Other designations are the same as in Table 1.